Tirzepatide Dosage Calculator & Research Doses

1Set Up Your Mix

20 mg/mL · 20000 mcg/mL

1. Pick your peptide

2. How much peptide is in the vial? It's printed on the label — usually something like 5 mg

3. How much water are you adding? More water makes each dose easier to measure

4. How much do you want per dose?

All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — TirzepatideYour Answer

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25Draw To This Line

0.25That's This Many mL

6Doses In The Vial

30 mg ÷ 1.5 mL = 20 mg/mL → 5 mg ÷ 20 mg/mL = 0.25 mL → × 100 = 25 units—

Looks good. Draw to 25 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 6 doses.

2Week-By-Week Plan — Tirzepatide

Approved-label escalation

When	Dose	How Often	How Many mL	Draw To	Number Of Doses
Initiation (wk 1–4)	2.5 mg	once weekly	0.125 mL	12.5 u	12 doses
Step 2	5 mg	once weekly	0.25 mL	25 u	6 doses
Step 3	7.5 mg	once weekly	0.375 mL	37.5 u	4 doses
Step 4	10 mg	once weekly	0.5 mL	50 u	3 doses
Trial maximum	15 mg	once weekly	0.75 mL	75 u	2 doses

Weeks until the top dose

20 weeks

Peptide used getting there

150 mg

Vials you'll need

5 × 30 mg

Once you're at the top dose

60 mg / 4 wk · 2 vials

Where this plan came from

A published dosing schedule

Where this came from: SURMOUNT-1 protocol and the approved label — 2.5 mg start, one step every four weeks. 5 mg, 10 mg and 15 mg are all recognised maintenance doses. Escalation stops at the assigned maintenance dose rather than always running to 15 mg.

3Common Doses — Tirzepatide

worked out for your mix

Level	Dose	How Often	How Many mL	Draw To	Doses In Vial
Weeks 1–4	2.5 mg	once weekly	0.125 mL	12.5 u	4	10 mg
Weeks 5–8	5 mg	once weekly	0.25 mL	25 u	4	20 mg
Weeks 9–12	7.5 mg	once weekly	0.375 mL	37.5 u	4	30 mg
Weeks 13–16	10 mg	once weekly	0.5 mL	50 u	4	40 mg
Weeks 17–20	12.5 mg	once weekly	0.625 mL	62.5 u	4	50 mg
Week 21 onward per 4 weeks from here on	15 mg	once weekly	0.75 mL	75 u	4	60 mg

Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About TirzepatideAbout This Peptide

Metabolic / Incretin

Also known as

Dual GIP/GLP-1 receptor agonist

Class

Metabolic / Incretin

Route

Subcutaneous

Half-life

~5 days

Evidence tier

Clinical

A dual incretin agonist. SURMOUNT-1 established the 5/10/15 mg maintenance arms with a four-week-per-step escalation from 2.5 mg.

Buy Tirzepatidethis peptide

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Where These Numbers Come From

Clinical — Human trial or approved-label dosing published

Tirzepatide once weekly for the treatment of obesity (SURMOUNT-1) Jastreboff AM, et al. New England Journal of Medicine, 2022

Pivotal obesity trial; source of the 5/10/15 mg arms and escalation schedule.

Find on PubMed ↗

Tirzepatide versus semaglutide once weekly in type 2 diabetes (SURPASS-2) Frías JP, et al. New England Journal of Medicine, 2021

Head-to-head dose-response against semaglutide.

Find on PubMed ↗

Newest Studies — —

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Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

Research Use Only — Confirm to Continue

Tirzepatide Dosage & Reconstitution

1Set Up Your Mix

Your Answer — TirzepatideYour Answer

2Week-By-Week Plan — Tirzepatide

3Common Doses — Tirzepatide

About TirzepatideAbout This Peptide

Where These Numbers Come From

Newest Studies — —

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