Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

5-Amino-1MQ Dosage & Reconstitution

5-amino-1-methylquinolinium. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: preclinical.

1Set Up Your Mix

16.667 mg/mL · 16667 mcg/mL

Your Answer — 5-Amino-1MQ

50 mg in 3 mL
15Draw To This Line
0.15That's This Many mL
20Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 15
50 mg ÷ 3 mL = 16.667 mg/mL  →  2.5 mg ÷ 16.667 mg/mL = 0.15 mL  →  × 100 = 15 units
Looks good. Draw to 15 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 20 doses.
When to dose
Time of dayAny time of day. Weekly compounds should be kept to the same day each week.
FoodWith or without food — it makes no meaningful difference.

These are long-acting and reach steady state over weeks, so a single day’s timing has little effect. Consistency matters more than the hour.

2Week-By-Week Plan — 5-Amino-1MQ

Two-day tolerance step
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Days 1–2 2.5 mg daily 0.15 mL 15 u 2 5 mg
Day 3 onward
per 4 weeks from here on
5 mg daily 0.3 mL 30 u 28 140 mg
Time until the top dose
2 days
Peptide used getting there
5 mg
Vials you'll need
1 × 50 mg
Once you're at the top dose
140 mg / 4 wk · 2.8 vials
Where this plan came from
An OptimalDosages protocol
Where this came from: Half strength for the first two days, then the standard daily amount. Some protocols keep the total at 5 mg but split it into two 2.5 mg doses across the day rather than one. At a 5 mg/mL mix that is 50 units twice instead of 100 units once.

3Common Doses — 5-Amino-1MQ

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Days 1–2 (tolerance) 2.5 mg 1× daily 0.15 mL 15 u 20 doses
Days 3 onward (standard) 5 mg 1× daily 0.3 mL 30 u 10 doses
Split dosing 2.5 mg 2× daily (5 mg total) 0.15 mL 15 u × 2 20 doses
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About 5-Amino-1MQ

Also known as
5-amino-1-methylquinolinium
Class
Metabolic / Incretin
Route
Subcutaneous
Half-life
Not well characterised
Evidence tier
Preclinical

A small-molecule NNMT inhibitor rather than a true peptide. Research data show reduced adiposity in diet-induced obesity models. Dosed daily, with the first two days at half strength to gauge tolerance before moving to the standard amount. Some protocols split the standard 5 mg into two 2.5 mg doses across the day instead. At a 5 mg/mL mix, 2.5 mg is 50 units and 5 mg is a full 100-unit syringe.

Buy 5-Amino-1MQ

Common Questions — 5-Amino-1MQ

How much bacteriostatic water do I add to a 50 mg vial of 5-Amino-1MQ?

Adding 3 mL of bacteriostatic water to a 50 mg vial gives 16.7 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.

What dose of 5-Amino-1MQ is used in research?

Published and reported figures for 5-Amino-1MQ run from 2.5 mg to 5 mg, typically 1× daily.5 mg to 5 mg, typically 1× daily.5 mg to 5 mg, typically 1× daily. This site lists each figure with the source it came from rather than giving a single recommended number.

How many units on the syringe is a 2.5 mg dose of 5-Amino-1MQ?

At 16.7 mg/mL, a 2.5 mg dose is 15 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 20 doses.

How strong is the evidence behind these 5-Amino-1MQ doses?

5-Amino-1MQ is graded preclinical. Laboratory and animal data only. No human dosing trials have been published. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.

Is there a 5-Amino-1MQ titration schedule?

Yes — Two-day tolerance step. 2 days The week-by-week table on this page converts each step into the exact amount to draw for your mix.

Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials
Small-molecule NNMT inhibitor reverses diet-induced obesity in mice Neelakantan H, et al. Biochemical Pharmacology, 2018
The primary preclinical result behind all downstream claims.
Find on PubMed ↗
Nicotinamide N-methyltransferase in metabolic regulation Kraus D, et al. Nature, 2014
Establishes NNMT as a metabolic target.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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