Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

AOD-9604 Dosage & Reconstitution

hGH fragment 176-191. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: clinical.

1Set Up Your Mix

2.5 mg/mL · 2500 mcg/mL

Your Answer — AOD-9604

5 mg in 2 mL
12Draw To This Line
0.12That's This Many mL
16Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 12
5 mg ÷ 2 mL = 2.5 mg/mL  →  300 mcg ÷ 2.5 mg/mL = 0.12 mL  →  × 100 = 12 units
Looks good. Draw to 12 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 16 doses.
When to dose
Time of dayOn an empty stomach, most often in the morning.
FoodFasted — leave about 2 hours after eating.

AOD-9604 is a fragment of growth hormone and the same reasoning applies: food raises insulin, which works against the lipolytic effect it is studied for.

2Week-By-Week Plan — AOD-9604

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Weeks 1–2 300 mcg daily 0.12 mL 12 u 14 4.2 mg
Week 3 onward
per 4 weeks from here on
500 mcg daily 0.2 mL 20 u 28 14 mg
Time until the top dose
2 weeks
Peptide used getting there
4.2 mg
Vials you'll need
1 × 5 mg
Once you're at the top dose
14 mg / 4 wk · 2.8 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — AOD-9604

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Commonly reported 300 mcg 1× daily 0.12 mL 12 u 16 doses
Upper reported 500 mcg 1× daily 0.2 mL 20 u 10 doses
Trial dose1–30 mg daily, 12 wk Set by body weight — can't be turned into a single amount to draw
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About AOD-9604

Metabolic / Incretin
Also known as
hGH fragment 176-191
Class
Metabolic / Incretin
Route
Subcutaneous
Half-life
Short (<1 h)
Evidence tier
Clinical

A C-terminal fragment of human growth hormone investigated as an anti-obesity agent. Human trials were conducted, but efficacy on weight endpoints was not compelling enough to advance, which is itself informative.

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Common Questions — AOD-9604

How much bacteriostatic water do I add to a 5 mg vial of AOD-9604?

Adding 2 mL of bacteriostatic water to a 5 mg vial gives 2.5 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.

What dose of AOD-9604 is used in research?

Published and reported figures for AOD-9604 run from 300 mcg to 500 mcg, typically 1× daily. This site lists each figure with the source it came from rather than giving a single recommended number.

How many units on the syringe is a 300 mcg dose of AOD-9604?

At 2.5 mg/mL, a 300 mcg dose is 12 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 16 doses.

How strong is the evidence behind these AOD-9604 doses?

AOD-9604 is graded clinical. Human trial or approved-label dosing has been published for this compound. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.

Where These Numbers Come From

Clinical — Human trial or approved-label dosing published
The effect of AOD9604 on body composition in obese subjects Heffernan MA, et al. and subsequent Metabolic Pharmaceuticals trial reports, 2000s
Human dosing data plus the negative efficacy signal.
Find on PubMed ↗
The effects of human GH and its lipolytic fragment on lipid metabolism Heffernan M, et al. Endocrinology, 2001
Mechanistic basis for the lipolytic claim in preclinical models.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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