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Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

Thymosin Alpha-1 Dosage & Reconstitution

Tα1, Thymalfasin, Zadaxin. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: clinical.

1Set Up Your Mix

3.333 mg/mL · 3333 mcg/mL
All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — Thymosin Alpha-1Your Answer

24Draw To This Line
0.24That's This Many mL
6Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 24
5 mg ÷ 1.5 mL = 3.333 mg/mL  →  0.8 mg ÷ 3.333 mg/mL = 0.24 mL  →  × 100 = 24 units
Looks good. Draw to 24 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 6 doses.

2Week-By-Week Plan — Thymosin Alpha-1

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Label dose 1.6 mg 2× weekly 0.48 mL 48 u 3 doses
Lower reported 0.8 mg 2× weekly 0.24 mL 24 u 6 doses
Higher reported 3.2 mg 2× weekly 0.96 mL 96 u 1 doses
Weeks until the top dose
4 weeks
Peptide used getting there
9.6 mg
Vials you'll need
2 × 5 mg
Once you're at the top dose
25.6 mg / 4 wk · 5.12 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — Thymosin Alpha-1

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Weeks 1–2 0.8 mg twice weekly 0.24 mL 24 u 4 3.2 mg
Weeks 3–4 1.6 mg twice weekly 0.48 mL 48 u 4 6.4 mg
Week 5 onward
per 4 weeks from here on
3.2 mg twice weekly 0.96 mL 96 u 8 25.6 mg
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About Thymosin Alpha-1About This Peptide

Immune & Anti-microbial
Also known as
Tα1, Thymalfasin, Zadaxin
Class
Immune & Anti-microbial
Route
Subcutaneous
Half-life
~2 h
Evidence tier
Clinical

A thymic peptide approved in a number of countries as an immunomodulator, principally as adjunct therapy in chronic hepatitis B and C. One of the better-evidenced compounds here, with a defined label dose.

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Where These Numbers Come From

Clinical — Human trial or approved-label dosing published
Thymosin alpha 1 — biological activities and clinical applications Garaci E, et al. Annals of the New York Academy of Sciences / Expert Opinion, 2007–2012
Consolidated clinical review including the 1.6 mg twice-weekly standard.
Find on PubMed ↗
Thymalfasin in chronic hepatitis B — meta-analysis Various, Journal of Viral Hepatitis, 2000s
Aggregate efficacy data at the label dose.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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