SS-31 Dosage Calculator & Research Doses

1Set Up Your Mix

60 mg/mL · 60000 mcg/mL

1. Pick your peptide

2. How much peptide is in the vial? It's printed on the label — usually something like 5 mg

3. How much water are you adding? More water makes each dose easier to measure

4. How much do you want per dose?

All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — SS-31Your Answer

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33.3Draw To This Line

0.333That's This Many mL

1Doses In The Vial

30 mg ÷ 0.5 mL = 60 mg/mL → 20 mg ÷ 60 mg/mL = 0.333 mL → × 100 = 33.3 units—

Looks good. Draw to 33.3 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 1 doses.

2Week-By-Week Plan — SS-31

Start low, work up

When	Dose	How Often	How Many mL	Draw To	Number Of Doses
Trial low	4 mg	1× daily	0.067 mL	6.7 u	7 doses
Trial mid	20 mg	1× daily	0.333 mL	33.3 u	1 doses
Trial high	40 mg	1× daily	0.667 mL	66.7 u	— doses
Trial max	60 mg	1× daily	1 mL	100 u	— doses

Weeks until the top dose

6 weeks

Peptide used getting there

896 mg

Vials you'll need

30 × 30 mg

Once you're at the top dose

1680 mg / 4 wk · 56 vials

Where this plan came from

Built from this peptide's dose range

Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — SS-31

worked out for your mix

Level	Dose	How Often	How Many mL	Draw To	Doses In Vial
Weeks 1–2	4 mg	daily	0.067 mL	6.7 u	14	56 mg
Weeks 3–4	20 mg	daily	0.333 mL	33.3 u	14	280 mg
Weeks 5–6	40 mg	daily	0.667 mL	66.7 u	14	560 mg
Week 7 onward per 4 weeks from here on	60 mg	daily	1 mL	100 u	28	1680 mg

Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About SS-31About This Peptide

Mitochondrial

Also known as

Elamipretide, Bendavia, MTP-131

Class

Mitochondrial

Route

Subcutaneous

Half-life

~2–3 h

Evidence tier

Clinical

A cardiolipin-targeting mitochondrial peptide — the only compound in this class with substantial registered human trial data, across Barth syndrome, primary mitochondrial myopathy and dry AMD. Results have been mixed, with several missed primary endpoints.

Buy SS-31this peptide

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Where These Numbers Come From

Clinical — Human trial or approved-label dosing published

Elamipretide in primary mitochondrial myopathy (MMPOWER-3) Karaa A, et al. Neurology, 2023

The largest registered trial; note the missed primary endpoint.

Find on PubMed ↗

Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane Szeto HH. AAPS Journal, 2006

Foundational mechanism paper for the SS peptide series.

Find on PubMed ↗

Elamipretide binds cardiolipin and improves mitochondrial cristae Birk AV, et al. Journal of the American Society of Nephrology, 2013

Structural mechanism via cardiolipin binding.

Find on PubMed ↗

Newest Studies — —

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Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

Research Use Only — Confirm to Continue

SS-31 Dosage & Reconstitution

1Set Up Your Mix

Your Answer — SS-31Your Answer

2Week-By-Week Plan — SS-31

3Common Doses — SS-31

About SS-31About This Peptide

Where These Numbers Come From

Newest Studies — —

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