Research Use Only — Confirm to Continue

OptimalDosages.com publishes reference material for laboratory and educational use. Nothing here is medical advice, a prescription, or a recommendation for human administration.

By continuing you confirm you are 21 or older and that you are accessing this material in a research or educational capacity.

Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

Glutathione Dosage & Reconstitution

GSH, reduced glutathione. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: clinical.

1Set Up Your Mix

100 mg/mL · 100000 mcg/mL
All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — GlutathioneYour Answer

400Draw To This Line
4That's This Many mL
1Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 400
600 mg ÷ 6 mL = 100 mg/mL  →  400 mg ÷ 100 mg/mL = 4 mL  →  × 100 = 400 units
This dose is 400 units — more than a 1 mL syringe holds. Split it into two injections, or add less water when you mix.

2Week-By-Week Plan — Glutathione

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Low reported 200 mg 2–3× weekly 2 mL 200 u ⚠ 3 doses
Standard 400 mg 2–3× weekly 4 mL 400 u ⚠ 1 doses
Upper reported 600 mg 2–3× weekly 6 mL 600 u ⚠ 1 doses
Weeks until the top dose
4 weeks
Peptide used getting there
3000 mg
Vials you'll need
5 × 600 mg
Once you're at the top dose
6000 mg / 4 wk · 10 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — Glutathione

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Weeks 1–2 200 mg 2.5× weekly 2 mL 200 u ⚠ 5 1000 mg
Weeks 3–4 400 mg 2.5× weekly 4 mL 400 u ⚠ 5 2000 mg
Week 5 onward
per 4 weeks from here on
600 mg 2.5× weekly 6 mL 600 u ⚠ 10 6000 mg
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About GlutathioneAbout This Peptide

Mitochondrial
Also known as
GSH, reduced glutathione
Class
Mitochondrial
Route
Subcutaneous
Half-life
Short (minutes)
Evidence tier
Clinical

The principal endogenous intracellular antioxidant tripeptide. Widely administered in clinical settings; the evidence for parenteral supplementation improving outcomes in healthy subjects is thin.

Buy Glutathionethis peptide

Opens optimal-pep.com in a new tab

Where These Numbers Come From

Clinical — Human trial or approved-label dosing published
Glutathione — metabolism and physiological functions Forman HJ, Zhang H, Rinna A. Molecular Aspects of Medicine, 2009
Standard biochemical reference.
Find on PubMed ↗
Randomised controlled trial of oral glutathione supplementation Richie JP, et al. European Journal of Nutrition, 2015
One of the few controlled human supplementation trials.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

More peptides

Browse the full catalogue, or jump to a neighbouring compound.

SS-31

A cardiolipin-targeting mitochondrial peptide — the only compound in this class with substantial registered human trial data, acro…

Semax

A synthetic ACTH fragment analogue registered as a medicine in Russia for stroke and cognitive indications. Substantial Russian cl…

All 71 peptides

Every compound compared in one table: dose range, how often, half-life and evidence tier.