NAD+ Dosage Calculator & Research Doses

1Set Up Your Mix

100 mg/mL · 100000 mcg/mL

1. Pick your peptide

2. How much peptide is in the vial? It's printed on the label — usually something like 5 mg

3. How much water are you adding? More water makes each dose easier to measure

4. How much do you want per dose?

All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — NAD+Your Answer

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100Draw To This Line

1That's This Many mL

5Doses In The Vial

500 mg ÷ 5 mL = 100 mg/mL → 100 mg ÷ 100 mg/mL = 1 mL → × 100 = 100 units—

Looks good. Draw to 100 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 5 doses.

2Week-By-Week Plan — NAD+

Start low, work up

When	Dose	How Often	How Many mL	Draw To	Number Of Doses
Low reported (SC)	50 mg	1× daily	0.5 mL	50 u	10 doses
Standard (SC)	100 mg	1× daily	1 mL	100 u	5 doses
Upper reported range	250–1000 mg over several hours	periodic	Set by body weight — can't be turned into a single amount to draw

Weeks until the top dose

2 weeks

Peptide used getting there

700 mg

Vials you'll need

2 × 500 mg

Once you're at the top dose

2800 mg / 4 wk · 5.6 vials

Where this plan came from

Built from this peptide's dose range

Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — NAD+

worked out for your mix

Level	Dose	How Often	How Many mL	Draw To	Doses In Vial
Weeks 1–2	50 mg	daily	0.5 mL	50 u	14	700 mg
Week 3 onward per 4 weeks from here on	100 mg	daily	1 mL	100 u	28	2800 mg

Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About NAD+About This Peptide

Mitochondrial

Also known as

Nicotinamide adenine dinucleotide

Class

Mitochondrial

Route

Subcutaneous

Half-life

Rapid clearance

Evidence tier

Limited

A coenzyme rather than a peptide. Direct NAD+ administration is bioavailability-limited and often poorly tolerated (stinging, flushing, nausea). Most rigorous human research uses precursors — NR or NMN — rather than NAD+ itself.

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Where These Numbers Come From

Limited — Sparse, single-programme, or community-reported figures

NAD+ metabolism and its roles in cellular processes during ageing Covarrubias AJ, et al. Nature Reviews Molecular Cell Biology, 2021

The definitive current review of NAD+ biology and where the evidence actually stands.

Find on PubMed ↗

Nicotinamide riboside supplementation in humans — dose escalation Trammell SAJ, et al. Nature Communications, 2016

Human PK for the precursor route, which is far better characterised than direct NAD+.

Find on PubMed ↗

Chronic nicotinamide riboside supplementation is well tolerated Martens CR, et al. Nature Communications, 2018

Human safety and tolerability at defined doses.

Find on PubMed ↗

Newest Studies — —

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Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

Research Use Only — Confirm to Continue

NAD+ Dosage & Reconstitution

1Set Up Your Mix

Your Answer — NAD+Your Answer

2Week-By-Week Plan — NAD+

3Common Doses — NAD+

About NAD+About This Peptide

Where These Numbers Come From

Newest Studies — —

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