1Set Up Your Mix
13.333 mg/mL · 13333 mcg/mLYour Answer — MOTS-c
40 mg in 3 mLThe studies behind this compound did not test timing or food state as variables, so we are not going to invent a rule. Pick a time you can keep to consistently.
2Week-By-Week Plan — MOTS-c
Two protocols — pick one, do not combine them| When | Dose | How Often | How Many mL | Draw To | Number Of Doses | Peptide Used |
|---|---|---|---|---|---|---|
| Option A · once a week a single 5 mg injection each week |
5 mg | once weekly | 0.375 mL | 37.5 u | 1 | 5 mg |
| Option B · daily, 5 on 2 off 1 mg a day for five days, then two days off |
1 mg | 5× weekly | 0.075 mL | 7.5 u | 5 | 5 mg |
3Common Doses — MOTS-c
worked out for your mix| Level | Dose | How Often | How Many mL | Draw To | Doses In Vial |
|---|---|---|---|---|---|
| Weekly protocol | 5 mg | once weekly | 0.375 mL | 37.5 u | 8 doses |
| Daily protocol | 1 mg | 5× weekly (5 on, 2 off) | 0.075 mL | 7.5 u | 40 doses |
About MOTS-c
MitochondrialA mitochondrial-derived peptide acting via AMPK on insulin sensitivity and metabolic homeostasis. Genuinely interesting mechanism with solid research data and human observational correlations, but no human dosing trials.
Buy MOTS-c
SyringesU-100 insulin · 1 mL · 29–31G
Alcohol wipes70% isopropyl prep pads
Serum base — for topical mixesHyaluronic acid serum for mixing peptides into a serum
Electric cooler caseTSA-approved travel cooler — keeps mixed vials at fridge temperature
Storage caseHard carry case for vialsPaid affiliate links.
Common Questions — MOTS-c
How much bacteriostatic water do I add to a 10 mg vial of MOTS-c?
Adding 2 mL of bacteriostatic water to a 10 mg vial gives 5 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.
What dose of MOTS-c is used in research?
Published and reported figures for MOTS-c on these protocols are 5 mg once weekly, or 1 mg a day on a five-days-on two-days-off pattern. This site lists each figure with the source it came from rather than giving a single recommended number.
How many units on the syringe is a 5 mg dose of MOTS-c?
At 5 mg/mL, a 5 mg dose is 100 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 2 doses.
How strong is the evidence behind these MOTS-c doses?
MOTS-c is graded preclinical. Laboratory and animal data only. No human dosing trials have been published. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.