LY3437943, triple GIP/GLP-1/glucagon agonist. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: clinical.
These are long-acting and reach steady state over weeks, so a single day’s timing has little effect. Consistency matters more than the hour.
| When | Dose | How Often | How Many mL | Draw To | Number Of Doses | Peptide Used |
|---|---|---|---|---|---|---|
| Week 1 let your system adjust |
1 mg | once weekly | 0.1 mL | 10 u | 1 | 1 mg |
| Week 2 | 2 mg | once weekly | 0.2 mL | 20 u | 1 | 2 mg |
| Weeks 3–6 most stop here +1 mg each week — most people stop somewhere in this band |
3 → 6 mg | once weekly | 0.3 → 0.6 mL | 30 → 60 u | 4 | 18 mg |
| Weeks 7–12 only if 6 mg was not enough — +1 mg weekly to the 12 mg ceiling |
7 → 12 mg | once weekly | 0.7 → 1.2 mL | 70 → 120 u ⚠ | 6 | 57 mg |
| Maintenance whatever dose you settled on — 5 mg shown as the typical case |
5 mg | once weekly | 0.5 mL | 50 u | 4 | 20 mg |
| Level | Dose | How Often | How Many mL | Draw To | Doses In Vial |
|---|---|---|---|---|---|
| Starting dose | 1 mg | once weekly | 0.1 mL | 10 u | 10 doses |
| Where most settle | 4 mg | once weekly | 0.4 mL | 40 u | 2 doses |
| Where most settle | 6 mg | once weekly | 0.6 mL | 60 u | 1 doses |
| Phase 2 arm | 8 mg | once weekly | 0.8 mL | 80 u | 1 doses |
| Phase 2 ceiling | 12 mg | once weekly | 1.2 mL | 120 u ⚠ | — doses |
A triple-receptor agonist in ongoing phase 3 development. Phase 2 data reported dose-dependent weight reduction up to 12 mg weekly. In practice most people settle at 4–6 mg once they reach the effect they were after — going higher tends to add side effects rather than results. Not approved anywhere; long-term safety is not established.
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Adding 1 mL of bacteriostatic water to a 10 mg vial gives 10 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.
Published and reported figures for Retatrutide run from 1 mg to 12 mg, typically once weekly. This site lists each figure with the source it came from rather than giving a single recommended number.
At 10 mg/mL, a 1 mg dose is 10 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 10 doses.
Retatrutide is graded clinical. Human trial or approved-label dosing has been published for this compound. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.
Yes — Weekly 1 mg step-up — most settle at 4–6 mg. 4–6 weeks for most people The week-by-week table on this page converts each step into the exact amount to draw for your mix.
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Every compound compared in one table: dose range, how often, half-life and evidence tier.