Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

MGF Dosage & Reconstitution

Mechano Growth Factor, IGF-1Ec splice variant. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: preclinical.

1Set Up Your Mix

1.667 mg/mL · 1667 mcg/mL

Your Answer — MGF

5 mg in 3 mL
12Draw To This Line
0.12That's This Many mL
25Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 12
5 mg ÷ 3 mL = 1.667 mg/mL  →  200 mcg ÷ 1.667 mg/mL = 0.12 mL  →  × 100 = 12 units
Looks good. Draw to 12 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 25 doses.
When to dose
Time of dayNo particular time of day has been established.
FoodNo fasting requirement has been established.

The studies behind this compound did not test timing or food state as variables, so we are not going to invent a rule. Pick a time you can keep to consistently.

2Week-By-Week Plan — MGF

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Weeks 1–2 200 mcg daily 0.12 mL 12 u 14 2.8 mg
Weeks 3–4 300 mcg daily 0.18 mL 18 u 14 4.2 mg
Week 5 onward
per 4 weeks from here on
400 mcg daily 0.24 mL 24 u 28 11.2 mg
Time until the top dose
4 weeks
Peptide used getting there
7 mg
Vials you'll need
2 × 5 mg
Once you're at the top dose
11.2 mg / 4 wk · 2.24 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — MGF

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Low reported 200 mcg post-training 0.12 mL 12 u 25 doses
Standard 300 mcg post-training 0.18 mL 18 u 16 doses
Upper reported 400 mcg post-training 0.24 mL 24 u 12 doses
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About MGF

Growth Factor
Also known as
Mechano Growth Factor, IGF-1Ec splice variant
Class
Growth Factor
Route
Subcutaneous
Half-life
Minutes
Evidence tier
Preclinical

A splice variant of IGF-1 expressed in muscle after mechanical loading, implicated in satellite cell activation. Extremely short-lived unmodified.

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Common Questions — MGF

How much bacteriostatic water do I add to a 5 mg vial of MGF?

Adding 3 mL of bacteriostatic water to a 5 mg vial gives 1.67 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.

What dose of MGF is used in research?

Published and reported figures for MGF run from 200 mcg to 400 mcg, typically post-training. This site lists each figure with the source it came from rather than giving a single recommended number.

How many units on the syringe is a 200 mcg dose of MGF?

At 1.67 mg/mL, a 200 mcg dose is 12 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 25 doses.

How strong is the evidence behind these MGF doses?

MGF is graded preclinical. Laboratory and animal data only. No human dosing trials have been published. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.

Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials
Mechano growth factor and muscle satellite cell activation Goldspink G, et al. Journal of Anatomy / Journal of Physiology, 2002–2005
The originating body of work on the IGF-1Ec splice variant.
Find on PubMed ↗
MGF E-peptide and myoblast proliferation Yang SY, Goldspink G. FEBS Letters, 2002
In vitro mechanism for the satellite-cell claim.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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