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Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

IGF-1 LR3 Dosage & Reconstitution

Long R3 insulin-like growth factor-1. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: preclinical.

1Set Up Your Mix

0.167 mg/mL · 167 mcg/mL
All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — IGF-1 LR3Your Answer

24Draw To This Line
0.24That's This Many mL
25Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 24
1 mg ÷ 6 mL = 0.167 mg/mL  →  40 mcg ÷ 0.167 mg/mL = 0.24 mL  →  × 100 = 24 units
Looks good. Draw to 24 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 25 doses.

2Week-By-Week Plan — IGF-1 LR3

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Low reported 20 mcg 1× daily 0.12 mL 12 u 50 doses
Standard 40 mcg 1× daily 0.24 mL 24 u 25 doses
Upper reported 60 mcg 1× daily 0.36 mL 36 u 16 doses
Weeks until the top dose
4 weeks
Peptide used getting there
0.84 mg
Vials you'll need
1 × 1 mg
Once you're at the top dose
1.68 mg / 4 wk · 1.68 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — IGF-1 LR3

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Weeks 1–2 20 mcg daily 0.12 mL 12 u 14 0.28 mg
Weeks 3–4 40 mcg daily 0.24 mL 24 u 14 0.56 mg
Week 5 onward
per 4 weeks from here on
60 mcg daily 0.36 mL 36 u 28 1.68 mg
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About IGF-1 LR3About This Peptide

Growth Factor
Also known as
Long R3 insulin-like growth factor-1
Class
Growth Factor
Route
Subcutaneous
Half-life
~20–30 h
Evidence tier
Preclinical

An IGF-1 analogue engineered to resist binding-protein sequestration, giving far longer activity than native IGF-1. Carries genuine hypoglycaemia risk. Widely used as a cell-culture supplement; human research use is not supported by trial data.

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Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials
Insulin-like growth factor-I and muscle hypertrophy Adams GR, McCue SA. Journal of Applied Physiology, 1998
Mechanistic basis for the hypertrophy claim in preclinical models.
Find on PubMed ↗
Long-R3-IGF-I — properties and applications Francis GL, et al. Journal of Molecular Endocrinology, 1992
Characterises why the LR3 modification extends activity.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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