Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

IGF-1 DES Dosage & Reconstitution

DES(1-3) IGF-1. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: preclinical.

1Set Up Your Mix

0.333 mg/mL · 333 mcg/mL

Your Answer — IGF-1 DES

1 mg in 3 mL
15Draw To This Line
0.15That's This Many mL
20Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 15
1 mg ÷ 3 mL = 0.333 mg/mL  →  50 mcg ÷ 0.333 mg/mL = 0.15 mL  →  × 100 = 15 units
Looks good. Draw to 15 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 20 doses.
When to dose
Time of dayNo particular time of day has been established.
FoodNo fasting requirement has been established.

The studies behind this compound did not test timing or food state as variables, so we are not going to invent a rule. Pick a time you can keep to consistently.

2Week-By-Week Plan — IGF-1 DES

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Weeks 1–2 50 mcg daily 0.15 mL 15 u 14 0.7 mg
Weeks 3–4 100 mcg daily 0.3 mL 30 u 14 1.4 mg
Week 5 onward
per 4 weeks from here on
150 mcg daily 0.45 mL 45 u 28 4.2 mg
Time until the top dose
4 weeks
Peptide used getting there
2.1 mg
Vials you'll need
3 × 1 mg
Once you're at the top dose
4.2 mg / 4 wk · 4.2 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — IGF-1 DES

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Low reported 50 mcg 1× daily 0.15 mL 15 u 20 doses
Standard 100 mcg 1× daily 0.3 mL 30 u 10 doses
Upper reported 150 mcg 1× daily 0.45 mL 45 u 6 doses
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About IGF-1 DES

Growth Factor
Also known as
DES(1-3) IGF-1
Class
Growth Factor
Route
Subcutaneous
Half-life
~20–30 min
Evidence tier
Preclinical

A truncated IGF-1 variant with roughly tenfold higher potency at the receptor but a very short half-life, hence its reputation as a localised agent. Preclinical only.

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Common Questions — IGF-1 DES

How much bacteriostatic water do I add to a 1 mg vial of IGF-1 DES?

Adding 3 mL of bacteriostatic water to a 1 mg vial gives 0.333 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.

What dose of IGF-1 DES is used in research?

Published and reported figures for IGF-1 DES run from 50 mcg to 150 mcg, typically 1× daily. This site lists each figure with the source it came from rather than giving a single recommended number.

How many units on the syringe is a 50 mcg dose of IGF-1 DES?

At 0.333 mg/mL, a 50 mcg dose is 15 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 20 doses.

How strong is the evidence behind these IGF-1 DES doses?

IGF-1 DES is graded preclinical. Laboratory and animal data only. No human dosing trials have been published. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.

Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials
DES(1-3)IGF-I — enhanced potency and reduced binding protein affinity Ballard FJ, et al. Journal of Endocrinology, 1989–1996
Establishes the potency and half-life profile.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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