IGF-1 DES Dosage Calculator & Research Doses

1Set Up Your Mix

0.4 mg/mL · 400 mcg/mL

1. Pick your peptide

2. How much peptide is in the vial? It's printed on the label — usually something like 5 mg

3. How much water are you adding? More water makes each dose easier to measure

4. How much do you want per dose?

All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — IGF-1 DESYour Answer

—

25Draw To This Line

0.25That's This Many mL

10Doses In The Vial

1 mg ÷ 2.5 mL = 0.4 mg/mL → 100 mcg ÷ 0.4 mg/mL = 0.25 mL → × 100 = 25 units—

Looks good. Draw to 25 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 10 doses.

2Week-By-Week Plan — IGF-1 DES

Start low, work up

When	Dose	How Often	How Many mL	Draw To	Number Of Doses
Low reported	50 mcg	1× daily	0.125 mL	12.5 u	20 doses
Standard	100 mcg	1× daily	0.25 mL	25 u	10 doses
Upper reported	150 mcg	1× daily	0.375 mL	37.5 u	6 doses

Weeks until the top dose

4 weeks

Peptide used getting there

2.1 mg

Vials you'll need

3 × 1 mg

Once you're at the top dose

4.2 mg / 4 wk · 4.2 vials

Where this plan came from

Built from this peptide's dose range

Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — IGF-1 DES

worked out for your mix

Level	Dose	How Often	How Many mL	Draw To	Doses In Vial
Weeks 1–2	50 mcg	daily	0.125 mL	12.5 u	14	0.7 mg
Weeks 3–4	100 mcg	daily	0.25 mL	25 u	14	1.4 mg
Week 5 onward per 4 weeks from here on	150 mcg	daily	0.375 mL	37.5 u	28	4.2 mg

Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About IGF-1 DESAbout This Peptide

Growth Factor

Also known as

DES(1-3) IGF-1

Class

Growth Factor

Route

Subcutaneous

Half-life

~20–30 min

Evidence tier

Preclinical

A truncated IGF-1 variant with roughly tenfold higher potency at the receptor but a very short half-life, hence its reputation as a localised agent. Preclinical only.

Buy IGF-1 DESthis peptide

Opens optimal-pep.com in a new tab

Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials

DES(1-3)IGF-I — enhanced potency and reduced binding protein affinity Ballard FJ, et al. Journal of Endocrinology, 1989–1996

Establishes the potency and half-life profile.

Find on PubMed ↗

Newest Studies — —

—

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

Research Use Only — Confirm to Continue

IGF-1 DES Dosage & Reconstitution