Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

Humanin Dosage & Reconstitution

Body Protection Compound 157, PL 14736. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: preclinical.

1Set Up Your Mix

5 mg/mL · 5000 mcg/mL

Your Answer — Humanin

10 mg in 2 mL
10Draw To This Line
0.1That's This Many mL
20Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 10
10 mg ÷ 2 mL = 5 mg/mL  →  500 mcg ÷ 5 mg/mL = 0.1 mL  →  × 100 = 10 units
Looks good. Draw to 10 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 20 doses.
When to dose
Time of dayNo particular time of day has been established.
FoodNo fasting requirement has been established.

The studies behind this compound did not test timing or food state as variables, so we are not going to invent a rule. Pick a time you can keep to consistently.

2Week-By-Week Plan — Humanin

Step up from 500 mcg
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Weeks 1–2
start here
500 mcg daily 0.1 mL 10 u 14 7 mg
Weeks 3–4 1 mg daily 0.2 mL 20 u 14 14 mg
Week 5 onward most stop here
most stay here
2 mg daily 0.4 mL 40 u 14 28 mg
Time to get there
4 weeks to the upper dose
Peptide used reaching that
21 mg
Vials you'll need
3 × 10 mg
Ongoing, once you settle
28 mg / 4 wk · 2.8 vials
Where this plan came from
A published protocol
Where this came from: OptimalDosages protocol.

3Common Doses — Humanin

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Start 500 mcg daily 0.1 mL 10 u 20 doses
Mid 1 mg daily 0.2 mL 20 u 10 doses
Upper 2 mg daily 0.4 mL 40 u 5 doses
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About BPC-157

Tissue Repair & Recovery
Also known as
HN, mitochondrial-derived peptide
Class
Mitochondrial
Route
Subcutaneous
Half-life
Short (analogues longer)
Evidence tier
Preclinical

A mitochondrial-derived peptide, from the same family as MOTS-c. Preclinical work examines cytoprotection, metabolic signalling and neuronal survival models. Most published research uses potent analogues such as HNG rather than native humanin, and dosing figures do not transfer cleanly between the two. No human dosing trials.

Buy Humanin

Common Questions — Humanin

How much bacteriostatic water do I add to a 10 mg vial of Humanin?

Adding 2 mL of bacteriostatic water to a 10 mg vial gives 5 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.

What dose of Humanin is used in research?

Published and reported figures for Humanin on this protocol run from 500 mcg to 2 mg daily, stepping up over four weeks. This site lists each figure with the source it came from rather than giving a single recommended number.

How many units on the syringe is a 500 mcg dose of Humanin?

At 5 mg/mL, a 500 mcg dose is 10 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 20 doses.

How strong is the evidence behind these Humanin doses?

Humanin is graded preclinical. Laboratory and animal data only. No human dosing trials have been published. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.

Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials
Humanin: a mitochondrial-derived peptide in cytoprotection Lee C, Yen K, Cohen P. Trends in Endocrinology and Metabolism, 2013
The standard overview of humanin biology and the analogue problem.
Find on PubMed ↗
MOTS-c and humanin in metabolic regulation Kim SJ, et al. Cell Metabolism literature
Places humanin alongside MOTS-c, which is the comparison most people want.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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