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Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

KPV Dosage & Reconstitution

Lys-Pro-Val (α-MSH 11-13). Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: preclinical.

1Set Up Your Mix

1.667 mg/mL · 1667 mcg/mL
All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — KPVYour Answer

24Draw To This Line
0.24That's This Many mL
25Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 24
10 mg ÷ 6 mL = 1.667 mg/mL  →  400 mcg ÷ 1.667 mg/mL = 0.24 mL  →  × 100 = 24 units
Looks good. Draw to 24 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 25 doses.

2Week-By-Week Plan — KPV

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Low reported 200 mcg 1× daily 0.12 mL 12 u 50 doses
Standard 400 mcg 1× daily 0.24 mL 24 u 25 doses
Upper 500 mcg 1× daily 0.3 mL 30 u 20 doses
Weeks until the top dose
4 weeks
Peptide used getting there
8.4 mg
Vials you'll need
1 × 10 mg
Once you're at the top dose
14 mg / 4 wk · 1.4 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — KPV

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Weeks 1–2 200 mcg daily 0.12 mL 12 u 14 2.8 mg
Weeks 3–4 400 mcg daily 0.24 mL 24 u 14 5.6 mg
Week 5 onward
per 4 weeks from here on
500 mcg daily 0.3 mL 30 u 28 14 mg
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About KPVAbout This Peptide

Tissue Repair & Recovery
Also known as
Lys-Pro-Val (α-MSH 11-13)
Class
Tissue Repair & Recovery
Route
Subcutaneous
Half-life
Short (minutes–hours)
Evidence tier
Preclinical

The C-terminal tripeptide of α-melanocyte-stimulating hormone, studied for anti-inflammatory activity in colitis and dermatitis models without the pigmentation effects of the full hormone.

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Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials
The tripeptide KPV: anti-inflammatory activity and mechanism Dalmasso G, et al. Gastroenterology, 2008
Demonstrates uptake via PepT1 and reduction of colonic inflammation in preclinical models.
Find on PubMed ↗
α-MSH and its C-terminal tripeptide in inflammation Brzoska T, et al. Endocrine Reviews, 2008
Situates KPV within melanocortin anti-inflammatory signalling.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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