Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

KPV Dosage & Reconstitution

Lys-Pro-Val (α-MSH 11-13). Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: preclinical.

1Set Up Your Mix

3.333 mg/mL · 3333 mcg/mL

Your Answer — KPV

10 mg in 3 mL
6Draw To This Line
0.06That's This Many mL
50Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 6
10 mg ÷ 3 mL = 3.333 mg/mL  →  200 mcg ÷ 3.333 mg/mL = 0.06 mL  →  × 100 = 6 units
Looks good. Draw to 6 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 50 doses.
When to dose
Time of dayNo particular time of day has been established.
FoodNo fasting requirement has been established.

The studies behind this compound did not test timing or food state as variables, so we are not going to invent a rule. Pick a time you can keep to consistently.

2Week-By-Week Plan — KPV

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Weeks 1–2 200 mcg daily 0.06 mL 6 u 14 2.8 mg
Weeks 3–4 400 mcg daily 0.12 mL 12 u 14 5.6 mg
Week 5 onward
per 4 weeks from here on
500 mcg daily 0.15 mL 15 u 28 14 mg
Time until the top dose
4 weeks
Peptide used getting there
8.4 mg
Vials you'll need
1 × 10 mg
Once you're at the top dose
14 mg / 4 wk · 1.4 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — KPV

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Low reported 200 mcg 1× daily 0.06 mL 6 u 50 doses
Standard 400 mcg 1× daily 0.12 mL 12 u 25 doses
Upper 500 mcg 1× daily 0.15 mL 15 u 20 doses
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About KPV

Tissue Repair & Recovery
Also known as
Lys-Pro-Val (α-MSH 11-13)
Class
Tissue Repair & Recovery
Route
Subcutaneous
Half-life
Short (minutes–hours)
Evidence tier
Preclinical

The C-terminal tripeptide of α-melanocyte-stimulating hormone, studied for anti-inflammatory activity in colitis and dermatitis models without the pigmentation effects of the full hormone.

Buy KPV

Common Questions — KPV

How much bacteriostatic water do I add to a 10 mg vial of KPV?

Adding 3 mL of bacteriostatic water to a 10 mg vial gives 3.33 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.

What dose of KPV is used in research?

Published and reported figures for KPV run from 200 mcg to 500 mcg, typically 1× daily. This site lists each figure with the source it came from rather than giving a single recommended number.

How many units on the syringe is a 200 mcg dose of KPV?

At 3.33 mg/mL, a 200 mcg dose is 6 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 50 doses.

How strong is the evidence behind these KPV doses?

KPV is graded preclinical. Laboratory and animal data only. No human dosing trials have been published. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.

Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials
The tripeptide KPV: anti-inflammatory activity and mechanism Dalmasso G, et al. Gastroenterology, 2008
Demonstrates uptake via PepT1 and reduction of colonic inflammation in preclinical models.
Find on PubMed ↗
α-MSH and its C-terminal tripeptide in inflammation Brzoska T, et al. Endocrine Reviews, 2008
Situates KPV within melanocortin anti-inflammatory signalling.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

Other tissue repair & recovery peptides

Compounds in the same class, or browse the full catalogue.

BPC-157

A pentadecapeptide fragment derived from a sequence in human gastric juice. The published record is almost entirely preclinical re…

TB-500

A synthetic fragment of thymosin beta-4, the actin-sequestering protein. Full-length Tβ4 reached human trials for dry eye and card…

All 72 peptides

Every compound compared in one table: dose range, how often, half-life and evidence tier.

Need this on one page to print, screenshot or send?

Make a dose card →