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BI 456906, GLP-1/glucagon dual agonist. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: clinical.
| When | Dose | How Often | How Many mL | Draw To | Number Of Doses | Peptide Used |
|---|---|---|---|---|---|---|
| Initiation | 0.6 mg | once weekly | 0.06 mL | 6 u | 16 doses | |
| Step | 2.4 mg | once weekly | 0.24 mL | 24 u | 4 doses | |
| Step | 3.6 mg | once weekly | 0.36 mL | 36 u | 2 doses | |
| Trial max | 6 mg | once weekly | 0.6 mL | 60 u | 1 doses |
| Level | Dose | How Often | How Many mL | Draw To | Doses In Vial | |
|---|---|---|---|---|---|---|
| Weeks 1–4 | 0.6 mg | once weekly | 0.06 mL | 6 u | 4 | 2.4 mg |
| Weeks 5–8 | 1.2 mg | once weekly | 0.12 mL | 12 u | 4 | 4.8 mg |
| Weeks 9–12 | 2.4 mg | once weekly | 0.24 mL | 24 u | 4 | 9.6 mg |
| Weeks 13–16 | 3.6 mg | once weekly | 0.36 mL | 36 u | 4 | 14.4 mg |
| Week 17 onward per 4 weeks from here on |
6 mg | once weekly | 0.6 mL | 60 u | 4 | 24 mg |
A dual GLP-1/glucagon receptor agonist in phase 3, with notable phase 2 results in MASH as well as obesity.
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An amylin analogue studied alone and in fixed combination with semaglutide (CagriSema). Escalation mirrors the GLP-1 pattern.…
A GLP-1/glucagon dual agonist developed primarily in Chinese phase 2/3 programmes.…
Every compound compared in one table: dose range, how often, half-life and evidence tier.