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Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

Sermorelin Dosage & Reconstitution

GHRH(1-29), Geref. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: clinical.

1Set Up Your Mix

0.833 mg/mL · 833 mcg/mL
All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — SermorelinYour Answer

24Draw To This Line
0.24That's This Many mL
25Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 24
5 mg ÷ 6 mL = 0.833 mg/mL  →  200 mcg ÷ 0.833 mg/mL = 0.24 mL  →  × 100 = 24 units
Looks good. Draw to 24 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 25 doses.

2Week-By-Week Plan — Sermorelin

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Low reported 100 mcg nightly 0.12 mL 12 u 50 doses
Standard 200 mcg nightly 0.24 mL 24 u 25 doses
Upper / historical 500 mcg nightly 0.6 mL 60 u 10 doses
Paediatric label30 mcg/kg nightly Set by body weight — can't be turned into a single amount to draw
Weeks until the top dose
4 weeks
Peptide used getting there
4.2 mg
Vials you'll need
1 × 5 mg
Once you're at the top dose
14 mg / 4 wk · 2.8 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — Sermorelin

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Weeks 1–2 100 mcg daily 0.12 mL 12 u 14 1.4 mg
Weeks 3–4 200 mcg daily 0.24 mL 24 u 14 2.8 mg
Week 5 onward
per 4 weeks from here on
500 mcg daily 0.6 mL 60 u 28 14 mg
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About SermorelinAbout This Peptide

GH Secretagogue
Also known as
GHRH(1-29), Geref
Class
GH Secretagogue
Route
Subcutaneous
Half-life
~10–20 min
Evidence tier
Clinical

The natural GHRH 1-29 fragment. Previously an approved agent for paediatric GH deficiency diagnosis and treatment before withdrawal from the US market for commercial reasons. Among the better-documented compounds in this class.

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Where These Numbers Come From

Clinical — Human trial or approved-label dosing published
Sermorelin: a better approach to management of adult-onset GH deficiency? Walker RF. Clinical Interventions in Aging, 2006
Reviews the rationale for GHRH-based over exogenous GH approaches.
Find on PubMed ↗
GHRH(1-29)NH2 in the diagnosis and treatment of GH deficiency Prakash A, Goa KL. BioDrugs, 1999
Consolidated clinical dosing from the approved-product era.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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