1Set Up Your Mix
5 mg/mL · 5000 mcg/mLYour Answer — Semaglutide
10 mg in 2 mLThese are long-acting and reach steady state over weeks, so a single day’s timing has little effect. Consistency matters more than the hour.
2Week-By-Week Plan — Semaglutide
Approved-label escalation| When | Dose | How Often | How Many mL | Draw To | Number Of Doses | Peptide Used |
|---|---|---|---|---|---|---|
| Weeks 1–4 | 0.25 mg | once weekly | 0.05 mL | 5 u | 4 | 1 mg |
| Weeks 5–8 | 0.5 mg | once weekly | 0.1 mL | 10 u | 4 | 2 mg |
| Weeks 9–12 | 1 mg | once weekly | 0.2 mL | 20 u | 4 | 4 mg |
| Weeks 13–16 | 1.7 mg | once weekly | 0.34 mL | 34 u | 4 | 6.8 mg |
| Week 17 onward per 4 weeks from here on |
2.4 mg | once weekly | 0.48 mL | 48 u | 4 | 9.6 mg |
3Common Doses — Semaglutide
worked out for your mix| Level | Dose | How Often | How Many mL | Draw To | Doses In Vial |
|---|---|---|---|---|---|
| Initiation (wk 1–4) | 0.25 mg | once weekly | 0.05 mL | 5 u | 40 doses |
| Escalation (wk 5–8) | 0.5 mg | once weekly | 0.1 mL | 10 u | 20 doses |
| Escalation (wk 9–12) | 1 mg | once weekly | 0.2 mL | 20 u | 10 doses |
| Escalation (wk 13–16) | 1.7 mg | once weekly | 0.34 mL | 34 u | 5 doses |
| Trial maintenance | 2.4 mg | once weekly | 0.48 mL | 48 u | 4 doses |
About Semaglutide
Metabolic / IncretinThe most extensively trialled compound in this database. Approved formulations follow a fixed escalation schedule to manage gastrointestinal tolerability; the figures below reflect the STEP obesity trial titration.
Buy Semaglutide
SyringesU-100 insulin · 1 mL · 29–31G
Alcohol wipes70% isopropyl prep pads
Serum base — for topical mixesHyaluronic acid serum for mixing peptides into a serum
Electric cooler caseTSA-approved travel cooler — keeps mixed vials at fridge temperature
Storage caseHard carry case for vialsPaid affiliate links.
Common Questions — Semaglutide
How much bacteriostatic water do I add to a 10 mg vial of Semaglutide?
Adding 2 mL of bacteriostatic water to a 10 mg vial gives 5 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.
What dose of Semaglutide is used in research?
Published and reported figures for Semaglutide run from 0.25 mg to 2.4 mg, typically once weekly.25 mg to 2.4 mg, typically once weekly.25 mg to 2.4 mg, typically once weekly. This site lists each figure with the source it came from rather than giving a single recommended number.
How many units on the syringe is a 0.25 mg dose of Semaglutide?
At 5 mg/mL, a 0.25 mg dose is 5 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 40 doses.
How strong is the evidence behind these Semaglutide doses?
Semaglutide is graded clinical. Human trial or approved-label dosing has been published for this compound. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.
Is there a Semaglutide titration schedule?
Yes — Approved-label escalation. The week-by-week table on this page converts each step into the exact amount to draw for your mix.