Melanotan II Dosage Calculator & Research Doses

1Set Up Your Mix

2 mg/mL · 2000 mcg/mL

1. Pick your peptide

2. How much peptide is in the vial? It's printed on the label — usually something like 5 mg

3. How much water are you adding? More water makes each dose easier to measure

4. How much do you want per dose?

All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — Melanotan IIYour Answer

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25Draw To This Line

0.25That's This Many mL

20Doses In The Vial

10 mg ÷ 5 mL = 2 mg/mL → 500 mcg ÷ 2 mg/mL = 0.25 mL → × 100 = 25 units—

Looks good. Draw to 25 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 20 doses.

2Week-By-Week Plan — Melanotan II

Loading and maintenance phases

When	Dose	How Often	How Many mL	Draw To	Number Of Doses
Loading (reported)	250 mcg	1× daily	0.125 mL	12.5 u	40 doses
Standard (reported)	500 mcg	1× daily	0.25 mL	25 u	20 doses
Maintenance (reported)	500 mcg	1–2× weekly	0.25 mL	25 u	20 doses

Weeks until the top dose

4 weeks

Peptide used getting there

10.5 mg

Vials you'll need

2 × 10 mg

Once you're at the top dose

4 mg / 4 wk · 0.4 vials

Where this plan came from

A commonly used protocol

Where this came from: Convention within the research community — not derived from a registered trial. Loading then maintenance. Note the safety record in the profile above — this compound has documented case reports of dysplastic naevi and melanoma associated with unregulated use.

3Common Doses — Melanotan II

worked out for your mix

Level	Dose	How Often	How Many mL	Draw To	Doses In Vial
Loading — weeks 1–2	250 mcg	daily	0.125 mL	12.5 u	14	3.5 mg
Loading — weeks 3–4	500 mcg	daily	0.25 mL	25 u	14	7 mg
Maintenance — week 5 onward per 4 weeks from here on	500 mcg	twice weekly	0.25 mL	25 u	8	4 mg

Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About Melanotan IIAbout This Peptide

Cosmetic & Dermal

Also known as

MT-2, cyclic α-MSH analogue

Class

Cosmetic & Dermal

Route

Subcutaneous

Half-life

~1–2 h

Evidence tier

Preclinical

A non-selective melanocortin agonist producing pigmentation, appetite suppression and erectile effects. Carries documented safety concerns: nausea, blood pressure changes, and case reports of dysplastic naevi and melanoma associated with unregulated use. Bremelanotide (PT-141) is the selectively developed descendant.

Buy Melanotan IIthis peptide

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Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials

Melanotan II — melanocortin agonist pharmacology in humans Dorr RT, et al. Life Sciences / Journal of Clinical Endocrinology, 1996–2000

The original human pharmacology and pigmentation data.

Find on PubMed ↗

Melanoma and dysplastic naevi associated with unregulated melanotan use Multiple case series, British Journal of Dermatology / JAMA Dermatology, 2009–2019

The safety literature. Read this before the efficacy literature.

Find on PubMed ↗

Newest Studies — —

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Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

Research Use Only — Confirm to Continue

Melanotan II Dosage & Reconstitution

1Set Up Your Mix

Your Answer — Melanotan IIYour Answer

2Week-By-Week Plan — Melanotan II

3Common Doses — Melanotan II

About Melanotan IIAbout This Peptide

Where These Numbers Come From

Newest Studies — —

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