Mazdutide Dosage Calculator & Chart

1Set Up Your Mix

5 mg/mL · 5000 mcg/mL

1. Pick your peptide

2. How much peptide is in the vial? It's printed on the label — usually something like 5 mg

3. How much water are you adding? More water makes each dose easier to measure

4. How much do you want per dose?

Your Answer — Mazdutide

5 mg in 1 mL

60Draw To This Line

0.6That's This Many mL

1Doses In The Vial

5 mg ÷ 1 mL = 5 mg/mL → 3 mg ÷ 5 mg/mL = 0.6 mL → × 100 = 60 units

Looks good. Draw to 60 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 1 doses.

When to dose

Time of dayAny time of day. Weekly compounds should be kept to the same day each week.

FoodWith or without food — it makes no meaningful difference.

These are long-acting and reach steady state over weeks, so a single day’s timing has little effect. Consistency matters more than the hour.

2Week-By-Week Plan — Mazdutide

Start low, work up

When	Dose	How Often	How Many mL	Draw To	Number Of Doses	Peptide Used
Weeks 1–4	3 mg	once weekly	0.6 mL	60 u	4	12 mg
Weeks 5–8	4.5 mg	once weekly	0.9 mL	90 u	4	18 mg
Weeks 9–12	6 mg	once weekly	1.2 mL	120 u ⚠	4	24 mg
Week 13 onward per 4 weeks from here on	9 mg	once weekly	1.8 mL	180 u ⚠	4	36 mg

Time until the top dose

12 weeks

Peptide used getting there

54 mg

Vials you'll need

11 × 5 mg

Once you're at the top dose

36 mg / 4 wk · 7.2 vials

Where this plan came from

Built from this peptide's dose range

Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — Mazdutide

worked out for your mix

Level	Dose	How Often	How Many mL	Draw To	Doses In Vial
Low arm	3 mg	once weekly	0.6 mL	60 u	1 doses
Mid arm	4.5 mg	once weekly	0.9 mL	90 u	1 doses
High arm	6 mg	once weekly	1.2 mL	120 u ⚠	— doses
Top arm	9 mg	once weekly	1.8 mL	180 u ⚠	— doses

Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About Mazdutide

Metabolic / Incretin

Also known as

IBI362, LY3305677, GLP-1/glucagon agonist

Class

Metabolic / Incretin

Route

Subcutaneous

Half-life

~5–6 days

Evidence tier

Clinical

A GLP-1/glucagon dual agonist developed primarily in Chinese phase 2/3 programmes.

Buy Mazdutide

Research Equipment

SyringesU-100 insulin · 1 mL · 29–31G

Alcohol wipes70% isopropyl prep pads

Serum base — for topical mixesHyaluronic acid serum for mixing peptides into a serum

Electric cooler caseTSA-approved travel cooler — keeps mixed vials at fridge temperature

Storage caseHard carry case for vials

Paid affiliate links.

Common Questions — Mazdutide

How much bacteriostatic water do I add to a 5 mg vial of Mazdutide?

Adding 1 mL of bacteriostatic water to a 5 mg vial gives 5 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.

What dose of Mazdutide is used in research?

Published and reported figures for Mazdutide run from 3 mg to 9 mg, typically once weekly. This site lists each figure with the source it came from rather than giving a single recommended number.

How many units on the syringe is a 3 mg dose of Mazdutide?

At 5 mg/mL, a 3 mg dose is 60 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 1 doses.

How strong is the evidence behind these Mazdutide doses?

Mazdutide is graded clinical. Human trial or approved-label dosing has been published for this compound. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.

Where These Numbers Come From

Clinical — Human trial or approved-label dosing published

Mazdutide in Chinese adults with overweight or obesity — phase 2 Ji L, et al. The Lancet Diabetes & Endocrinology, 2023/2024

Primary dose-ranging source.

Find on PubMed ↗

Newest Studies — —

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Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

Mazdutide Dosage & Reconstitution