Research Use Only — Confirm to Continue

OptimalDosages.com publishes reference material for laboratory and educational use. Nothing here is medical advice, a prescription, or a recommendation for human administration.

By continuing you confirm you are 21 or older and that you are accessing this material in a research or educational capacity.

Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

DSIP Dosage & Reconstitution

Delta Sleep-Inducing Peptide. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: limited.

1Set Up Your Mix

0.833 mg/mL · 833 mcg/mL
All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — DSIPYour Answer

24Draw To This Line
0.24That's This Many mL
25Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 24
5 mg ÷ 6 mL = 0.833 mg/mL  →  200 mcg ÷ 0.833 mg/mL = 0.24 mL  →  × 100 = 24 units
Looks good. Draw to 24 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 25 doses.

2Week-By-Week Plan — DSIP

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Low reported 100 mcg pre-sleep 0.12 mL 12 u 50 doses
Standard 200 mcg pre-sleep 0.24 mL 24 u 25 doses
Upper reported 300 mcg pre-sleep 0.36 mL 36 u 16 doses
Weeks until the top dose
4 weeks
Peptide used getting there
4.2 mg
Vials you'll need
1 × 5 mg
Once you're at the top dose
8.4 mg / 4 wk · 1.68 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — DSIP

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Weeks 1–2 100 mcg daily 0.12 mL 12 u 14 1.4 mg
Weeks 3–4 200 mcg daily 0.24 mL 24 u 14 2.8 mg
Week 5 onward
per 4 weeks from here on
300 mcg daily 0.36 mL 36 u 28 8.4 mg
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About DSIPAbout This Peptide

Cognitive & Neuro
Also known as
Delta Sleep-Inducing Peptide
Class
Cognitive & Neuro
Route
Subcutaneous
Half-life
~7–15 min
Evidence tier
Limited

A nonapeptide originally isolated from cerebral venous blood during induced sleep. Despite the name, controlled human sleep-architecture results have been inconsistent, and the compound has essentially no modern clinical development.

Buy DSIPthis peptide

Opens optimal-pep.com in a new tab

Where These Numbers Come From

Limited — Sparse, single-programme, or community-reported figures
Delta sleep-inducing peptide — isolation and characterisation Schoenenberger GA, Monnier M. PNAS, 1977
The discovery paper.
Find on PubMed ↗
DSIP in chronic insomnia and disturbed sleep Schneider-Helmert D. European Neurology / Sleep research, 1980s
Human sleep data; results are equivocal, which is the useful finding.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

More peptides

Browse the full catalogue, or jump to a neighbouring compound.

Cerebrolysin

Not a single peptide but a standardised mixture of low-molecular-weight peptides and amino acids of porcine origin. Approved in a …

PE-22-28

A shortened spadin analogue that blocks the TREK-1 potassium channel, proposed as a fast-acting antidepressant mechanism. Preclini…

All 71 peptides

Every compound compared in one table: dose range, how often, half-life and evidence tier.