PT-141 Dosage Calculator & Research Doses

1Set Up Your Mix

4 mg/mL · 4000 mcg/mL

1. Pick your peptide

2. How much peptide is in the vial? It's printed on the label — usually something like 5 mg

3. How much water are you adding? More water makes each dose easier to measure

4. How much do you want per dose?

All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — PT-141Your Answer

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25Draw To This Line

0.25That's This Many mL

10Doses In The Vial

10 mg ÷ 2.5 mL = 4 mg/mL → 1 mg ÷ 4 mg/mL = 0.25 mL → × 100 = 25 units—

Looks good. Draw to 25 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 10 doses.

2Week-By-Week Plan — PT-141

Start low, work up

When	Dose	How Often	How Many mL	Draw To	Number Of Doses
Label dose	1.75 mg	as needed, max 1×/24 h	0.438 mL	43.8 u	5 doses
Lower reported	1 mg	as needed	0.25 mL	25 u	10 doses
Trial upper	2 mg	as needed	0.5 mL	50 u	5 doses

Weeks until the top dose

4 weeks

Peptide used getting there

38.5 mg

Vials you'll need

4 × 10 mg

Once you're at the top dose

56 mg / 4 wk · 5.6 vials

Where this plan came from

Built from this peptide's dose range

Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — PT-141

worked out for your mix

Level	Dose	How Often	How Many mL	Draw To	Doses In Vial
Weeks 1–2	1 mg	daily	0.25 mL	25 u	14	14 mg
Weeks 3–4	1.75 mg	daily	0.438 mL	43.8 u	14	24.5 mg
Week 5 onward per 4 weeks from here on	2 mg	daily	0.5 mL	50 u	28	56 mg

Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About PT-141About This Peptide

Endocrine & Sexual Health

Also known as

Bremelanotide, Vyleesi

Class

Endocrine & Sexual Health

Route

Subcutaneous

Half-life

~2.7 h

Evidence tier

Clinical

An FDA-approved melanocortin-4 agonist for hypoactive sexual desire disorder in premenopausal women. The 1.75 mg label dose is well defined; nausea is the dominant adverse effect and transient blood pressure elevation is documented.

Buy PT-141this peptide

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Where These Numbers Come From

Clinical — Human trial or approved-label dosing published

Bremelanotide for hypoactive sexual desire disorder (RECONNECT) Kingsberg SA, et al. Obstetrics & Gynecology, 2019

The pivotal phase 3 trials establishing the 1.75 mg dose.

Find on PubMed ↗

Bremelanotide safety — blood pressure and nausea profile Clayton AH, et al. Journal of Sexual Medicine, 2019

The safety dataset behind the once-per-24-hour restriction.

Find on PubMed ↗

Newest Studies — —

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Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

Research Use Only — Confirm to Continue

PT-141 Dosage & Reconstitution

1Set Up Your Mix

Your Answer — PT-141Your Answer

2Week-By-Week Plan — PT-141

3Common Doses — PT-141

About PT-141About This Peptide

Where These Numbers Come From

Newest Studies — —

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