Oxytocin Dosage Calculator & Doses

Start very low and titrate by response. Sensitivity to oxytocin varies enormously between individuals. Some people respond strongly to a dose that others barely notice, and the response is not predictable from body weight or from experience with other compounds. Overdosing carries real risk — this is not a compound where more is better, and the effects of too much are not simply a stronger version of the effects of the right amount.

What we suggest instead. Begin well below the lowest figure in the table, give yourself time to see how you respond, and only move up if there is a clear reason to. If you notice a strong reaction at a low dose, that is your answer — stay there or go lower rather than working up to a number on a chart.

1Set Up Your Mix

1.667 mg/mL · 1667 mcg/mL

1. Pick your peptide

2. How much peptide is in the vial? It's printed on the label — usually something like 5 mg

3. How much water are you adding? More water makes each dose easier to measure

4. How much do you want per dose?

Your Answer — Oxytocin

5 mg in 3 mL

6Draw To This Line

0.06That's This Many mL

50Doses In The Vial

5 mg ÷ 3 mL = 1.667 mg/mL → 100 mcg ÷ 1.667 mg/mL = 0.06 mL → × 100 = 6 units

Looks good. Draw to 6 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 50 doses.

When to dose

Time of dayNo particular time of day has been established.

FoodNo fasting requirement has been established.

The studies behind this compound did not test timing or food state as variables, so we are not going to invent a rule. Pick a time you can keep to consistently.

2Week-By-Week Plan — Oxytocin

Gradual daily titration

When	Dose	How Often	How Many mL	Draw To	Number Of Doses	Peptide Used
Weeks 1-2 start here	100 mcg	daily	0.06 mL	6 u	14	1.4 mg
Weeks 3-4	200 mcg	daily	0.12 mL	12 u	14	2.8 mg
Weeks 5-6	300 mcg	daily	0.18 mL	18 u	14	4.2 mg
Weeks 7-8	400 mcg	daily	0.24 mL	24 u	14	5.6 mg
Weeks 9-12 onward most stop here typical upper limit in research protocols	500 mcg	daily	0.3 mL	30 u	28	14 mg

Time to get there

12 weeks to the 500 mcg target

Peptide used reaching that

14 mg

Vials you'll need

3 × 5 mg

Ongoing, once you settle

14 mg / 4 wk · 2.8 vials

Where this plan came from

A published protocol

Where this came from: The peptidedosages.com 5 mg protocol - 100 mcg daily, rising by 100 mcg every two weeks. Doses are in micrograms, not IU. Most published human work is intranasal; the subcutaneous figures here come from an educational protocol rather than a trial of this route. Oxytocin clears quickly, so effects are acute per dose.

3Common Doses — Oxytocin

worked out for your mix

Level	Dose	How Often	How Many mL	Draw To	Doses In Vial
Weeks 1-2 (start)	100 mcg	once daily	0.06 mL	6 u	50 doses
Weeks 3-4	200 mcg	once daily	0.12 mL	12 u	25 doses
Weeks 5-6	300 mcg	once daily	0.18 mL	18 u	16 doses
Weeks 7-8	400 mcg	once daily	0.24 mL	24 u	12 doses
Weeks 9-12 (target)	500 mcg	once daily	0.3 mL	30 u	10 doses

Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About Oxytocin

Endocrine & Sexual Health

Also known as

Pitocin

Class

Endocrine & Sexual Health

Route

Subcutaneous

Half-life

~1–6 min

Evidence tier

Clinical

A nonapeptide hormone studied for social bonding, stress, appetite and pain modulation. Dosed in micrograms, not IU - a 5 mg vial in 3 mL gives about 1.67 mg/mL, so one syringe unit is roughly 16.7 mcg. Most published human work is intranasal; the subcutaneous figures here come from educational protocols.

Buy Oxytocin

Research Equipment

SyringesU-100 insulin · 1 mL · 29–31G

Alcohol wipes70% isopropyl prep pads

Serum base — for topical mixesHyaluronic acid serum for mixing peptides into a serum

Electric cooler caseTSA-approved travel cooler — keeps mixed vials at fridge temperature

Storage caseHard carry case for vials

Paid affiliate links.

Common Questions — Oxytocin

How much bacteriostatic water do I add to a 5 mg vial of Oxytocin?

Adding 3 mL of bacteriostatic water to a 5 mg vial gives 1.67 mg/mL. That is the mix every number on this page is worked out from — change the water figure in the calculator and all the draw amounts update.

What dose of Oxytocin is used in research?

Published and reported figures for Oxytocin run from 12 IU to 40 IU, typically single dose. This site lists each figure with the source it came from rather than giving a single recommended number.

How many units on the syringe is a 12 iu dose of Oxytocin?

At 10 mg/mL, a 12 iu dose is 40 units on a 1 mL U-100 insulin syringe. One vial at that mix gives about 1 doses.

How strong is the evidence behind these Oxytocin doses?

Oxytocin is graded clinical. Human trial or approved-label dosing has been published for this compound. We grade every compound on this site so you can weigh the numbers accordingly — the full method is on our editorial policy page.

Where These Numbers Come From

Clinical — Human trial or approved-label dosing published

Oxytocin increases trust in humans Kosfeld M, et al. Nature, 2005

The originating intranasal social-cognition study; source of the 24 IU convention.

Find on PubMed ↗

Intranasal oxytocin — replication and methodological critique Leng G, Ludwig M. Biological Psychiatry, 2016

The essential corrective; questions whether intranasal dosing reaches the brain meaningfully at all.

Find on PubMed ↗

Newest Studies — —

—

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

Oxytocin Dosage & Reconstitution