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Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

Oxytocin Dosage & Reconstitution

Pitocin. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: clinical.

1Set Up Your Mix

10 mg/mL · 10000 mcg/mL
All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — OxytocinYour Answer

40Draw To This Line
0.4That's This Many mL
1Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 40
5 mg ÷ 0.5 mL = 10 mg/mL  →  12 IU ÷ 10 mg/mL = 0.4 mL  →  × 100 = 40 units
Looks good. Draw to 40 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 1 doses.

2Week-By-Week Plan — Oxytocin

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Standard reported 24 IU single dose 0.8 mL 80 u — doses
Low reported 12 IU single dose 0.4 mL 40 u 1 doses
Upper reported 40 IU single dose 1.333 mL 133.3 u ⚠ — doses
Weeks until the top dose
4 weeks
Peptide used getting there
168 mg
Vials you'll need
34 × 5 mg
Once you're at the top dose
373.33 mg / 4 wk · 74.67 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — Oxytocin

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Weeks 1–2 12 IU daily 0.4 mL 40 u 14 56 mg
Weeks 3–4 24 IU daily 0.8 mL 80 u 14 112 mg
Week 5 onward
per 4 weeks from here on
40 IU daily 1.333 mL 133.3 u ⚠ 28 373.33 mg
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About OxytocinAbout This Peptide

Endocrine & Sexual Health
Also known as
Pitocin
Class
Endocrine & Sexual Health
Route
Subcutaneous
Half-life
~1–6 min
Evidence tier
Clinical

A nonapeptide hormone. Long established as a clinical drug. The social-cognition research literature is large but has significant replication problems worth knowing about before reading any single result.

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Where These Numbers Come From

Clinical — Human trial or approved-label dosing published
Oxytocin increases trust in humans Kosfeld M, et al. Nature, 2005
The originating intranasal social-cognition study; source of the 24 IU convention.
Find on PubMed ↗
Intranasal oxytocin — replication and methodological critique Leng G, Ludwig M. Biological Psychiatry, 2016
The essential corrective; questions whether intranasal dosing reaches the brain meaningfully at all.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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