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Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

FOXO4-DRI Dosage & Reconstitution

FOXO4-D-Retro-Inverso peptide. Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: preclinical.

1Set Up Your Mix

20 mg/mL · 20000 mcg/mL
All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — FOXO4-DRIYour Answer

25Draw To This Line
0.25That's This Many mL
2Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 25
10 mg ÷ 0.5 mL = 20 mg/mL  →  5 mg ÷ 20 mg/mL = 0.25 mL  →  × 100 = 25 units
Looks good. Draw to 25 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 2 doses.

2Week-By-Week Plan — FOXO4-DRI

not applicable
No week-by-week plan for FOXO4-DRI. This one is dosed by body weight, comes ready-mixed, or only has a single dose reported — so there is nothing to work up through.

3Common Doses — FOXO4-DRI

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About FOXO4-DRIAbout This Peptide

Longevity & Bioregulator
Also known as
FOXO4-D-Retro-Inverso peptide
Class
Longevity & Bioregulator
Route
Subcutaneous
Half-life
Short
Evidence tier
Preclinical

A senolytic peptide that disrupts the FOXO4–p53 interaction, selectively triggering apoptosis in senescent cells. The research data are striking; there is no human dosing data whatsoever, and the mechanism is intrinsically cytotoxic.

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Where These Numbers Come From

Preclinical — Preclinical and in-vitro data only — no human dosing trials
Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging Baar MP, et al. Cell, 2017
The originating senolytic study; the sole substantive reference for this compound.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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