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Research Use Only · Dosing data compiled from published literature · Not for human or veterinary use

Epitalon Dosage & Reconstitution

Epithalon, Ala-Glu-Asp-Gly (AEDG). Work out exactly what to draw for your own mix, see the doses used in research, and follow a week-by-week plan. Evidence tier: limited.

1Set Up Your Mix

20 mg/mL · 20000 mcg/mL
All answers assume a standard 1 mL U-100 syringe, where 1 unit = 0.01 mL. That is the usual insulin syringe and the one every number here is based on.

Your Answer — EpitalonYour Answer

50Draw To This Line
0.5That's This Many mL
1Doses In The Vial
0102030405060708090100 U-100 syringe · 1 mL · 100 units draw to 50
10 mg ÷ 0.5 mL = 20 mg/mL  →  10 mg ÷ 20 mg/mL = 0.5 mL  →  × 100 = 50 units
Looks good. Draw to 50 units on a 1 mL syringe. That is an easy amount to measure, and this vial gives you 1 doses.

2Week-By-Week Plan — Epitalon

Start low, work up
WhenDoseHow OftenHow Many mLDraw ToNumber Of DosesPeptide Used
Short course low 5 mg daily ×10 days 0.25 mL 25 u 2 doses
Short course std 10 mg daily ×10 days 0.5 mL 50 u 1 doses
Extended course 5 mg daily ×20 days, 2×/yr 0.25 mL 25 u 2 doses
Weeks until the top dose
2 weeks
Peptide used getting there
70 mg
Vials you'll need
7 × 10 mg
Once you're at the top dose
280 mg / 4 wk · 28 vials
Where this plan came from
Built from this peptide's dose range
Where this came from: Built from the doses listed for this peptide below — start at the lowest and step up, using the studies cited on this page. Nobody publishes a week-by-week plan for this peptide, so we built one: the doses are the researched ones shown below, and we simply put them in order from lowest to highest. Treat it as a starting point, not an official schedule.

3Common Doses — Epitalon

worked out for your mix
LevelDoseHow OftenHow Many mLDraw ToDoses In Vial
Weeks 1–2 5 mg daily 0.25 mL 25 u 14 70 mg
Week 3 onward
per 4 weeks from here on
10 mg daily 0.5 mL 50 u 28 280 mg
Please read this. These numbers come from published research. They are here as reference, not as instructions. A lot of them come from lab studies rather than studies in people, and some of these peptides have never been given to a person at all.

About EpitalonAbout This Peptide

Longevity & Bioregulator
Also known as
Epithalon, Ala-Glu-Asp-Gly (AEDG)
Class
Longevity & Bioregulator
Route
Subcutaneous
Half-life
Very short
Evidence tier
Limited

A synthetic tetrapeptide from the Khavinson bioregulator programme, associated with telomerase activation and pineal regulation claims. The supporting literature is overwhelmingly from a single Russian research group, largely in journals with limited international peer review, and has not been independently replicated at scale.

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Where These Numbers Come From

Limited — Sparse, single-programme, or community-reported figures
Peptides and ageing — the Khavinson bioregulator programme Khavinson VK. Neuroendocrinology Letters, 2002 and subsequent
Primary programme reference. Read critically: single-group, limited independent replication.
Find on PubMed ↗
Effect of epitalon on telomerase activity and telomere length in human somatic cells Khavinson VK, et al. Bulletin of Experimental Biology and Medicine, 2003
The specific telomerase claim, in vitro.
Find on PubMed ↗
Pineal peptide preparation Epithalamin — long-term survival data Anisimov VN, et al. Mechanisms of Ageing and Development, 2003
The lifespan data underlying the anti-ageing framing.
Find on PubMed ↗

Newest Studies —

Not reviewed by us. This list is pulled straight from Europe PMC as papers are published. Nobody has checked whether these are any good, or whether they change anything above. The dose numbers on this page only ever change after a person reviews the evidence.

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